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Psychiatric Genetics provides the reader with a complete view of the methodological problems encountered in psychiatry genetics and proposes solutions to commonly occurring questions. The best European and American specialists have given a thorough review on the advantages and disadvantages of genetic epidemiological methods, the way to choose a genetic marker or a clinical interview and how to ascertain patients, unaffected relatives and controls and what should be the criteria to include a case or a control. New phenotypic methods are described focusing on candidate symptom and endophenotype approaches. Examples coming from cognitive neurosciences, biochemistry, electrophysiology and brain imaging techniques are reviewed. This book will serve as an essential handbook for psychiatrists, psychologists, and geneticists involved in the genetics of psychiatric disorders.

Authors: Leboyer, Marion ; Bellivier, Frank

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Table of Contents

1. Psychiatric Genetics: Overview on Achievements, Problems, Perspectives (pp. 03-20)
   Maier, Wolfgang
2. Analytical Methods Applied to Psychiatric Genetics (pp. 23-62)
   Grigorenko, Elenal L.; Pauls, David L.
3. Genetic Markers in Psychiatric Genetics (pp. 63-98)
   Bourgeron, Thomas; Giros, Bruno
4. Clinical Assessment in Psychiatric Genetics (pp. 99-126)
   Gorwood, Philip
5. Genetic Association Studies: Definition of Cases and Controls (pp. 127-142)
   Bellivier, Frank
6. Searching for Alternative Phenotypes in Psychiatric Genetics (pp. 145-162)
   Leboyer, Marion
7. Intermediate Cognitive Phenotypes Associated with Schizophrenia (pp. 163-198)
   Egan, Michael F.; Goldberg, Terry E.
8. Biochemical Endophenotypes in Personality Disorders (pp. 199-214)
   New, Antonia S.; Siever, Larry J.
9. Electrophysiological Phenotypes (pp. 215-226)
   Freedman, Robert
10. Brain Imaging as an Approach to Phenotype Characterization for Genetic Studies (pp. 227-248)
    Callicott, Joseph H.; Weinberger, Daniel R.
11. Psychiatric Genetics: Future and Prospects (pp. 251-266)
    Tsuang, Ming T.; Taylor, Levi; Faraone, Stephen V.

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