Imaging in Biological Research, Part B
posted in Enzymology |As these volumes were being completed, American Paul C. Lauterbur and Briton Sir Peter Mansfield won the 2003 Nobel Prize for medicine for discoveries leading to the development of MRI.
The Washington Post story on October 6, 2003 announced the accolade, noting: “Magnetic resonance imaging, or MRI, has become a routine method for medical diagnosis and treatment. It is used to examine almost all organs without need for surgery, but is especially valuable for detailed examination of the brain and spinal cord.” Unfortunately, the article overlooked the growing usefulness of this technique in basic research.
Authors have been selected based on research contributions in the area about which they have written and based on their ability to describe their methodological contributions in a clear and reproducible way. They have been encouraged to make use of graphics and comparisons to other methods, and to provide tricks and approaches that make it possible to adapt methods to other systems. MRI, along with other imaging methods, has made it possible to glance inside the living system. For patients, this may obviate the need for surgery; for researchers, it becomes a noninvasive method that enables the model systems to continue “doing what they do” without being disturbed. The value and potential of these techniques is enormous, and that is why these once clinical methods are finding their way to the laboratory.
Ed. P. Michael Conn
imaging-in-biological-research-part-b.pdf
Table of Contents
- Editors-In-Chief (Page ii)
- Contributors to Volume 386 (pp.vii-ix )
- Preface (Page xi)
- Methods In Enzymology (pp.xiii-xxxiv )
- Molecular and Functional Imaging of Cancer: Advances in MRI and MRS (pp1-58)
Arvind P. Pathak, Barjor Gimi, Kristine Glunde, Ellen Ackerstaff, Dmitri Artemov and Zaver M. Bhujwalla - A Modified Transorbital Baboon Model of Reperfused Stroke (pp60-73)
Anthony L. D’Ambrosio, Michael E. Sughrue, J. Mocco, William J. Mack, Ryan G. King, Shivani Agarwal and E. Sander Connolly, Jr. - MRI Investigations of Graft Rejection Following Organ Transplantation Using Rodent Models (pp73-105)
Yi-Jen L. Wu, Kazuya Sato, Qing Ye and Chien Ho - Structural and Functional Optical Imaging of Angiogenesis in Animal Models (pp105-122)
Richard L. Roberts and Pengnian Charles Lin - Cardiovascular Magnetic Resonance Imaging: Current Applications and Future Directions (pp122-148)
Milind Y. Desai, Joao A. Lima and David A. Bluemke - MRI of Animal Models of Brain Disease (pp149-177)
Louise van der Weerd, David L. Thomas, John S. Thornton and Mark F. Lythgoe - Magnetic Resonance Imaging in Animal Models of Pathologies (pp177-200)
Pasquina Marzola and Andrea Sbarbati - Application of Combined Magnetic Resonance Imaging and Histopathologic and Functional Studies for Evaluation of Aminoguanidine Following Traumatic Brain Injury in Rats (pp200-211)
Jia Lu and Shabbir Moochhala - Using 99mTc-sestamibi to Evaluate the Effects of a Chemosensitizer on P-glycoprotein in Multidrug-Resistant Carcinoma Cells (pp212-216)
Zhenwei Zhang, Xuemei Zhang, Hua Wu and Ming Zhao - Vascular-Targeted Nanoparticles for Molecular Imaging and Therapy (pp219-236)
Samira Guccione, King C. P. Li and Mark D. Bednarski - Production and Applications of Copper-64 Radiopharmaceuticals (pp237-261)
Xiankai Sun and Carolyn J. Anderson - Generation of DOTA-Conjugated Antibody Fragments for Radioimmunoimaging (pp262-275)
Peter M. Smith-Jones and David B. Solit - Preparation of Magnetically Labeled Cells for Cell Tracking by Magnetic Resonance Imaging (pp275-299)
Jeff W. M. Bulte, Ali S. Arbab, T. Douglas and J. A. Frank - The Application of Magnetic Resonance Imaging and Spectroscopy to Gene Therapy (pp303-313)
Kishore K. Bhakoo, Jimmy D. Bell, I. Jane Cox and Simon D. Taylor-Robinson - Voxelation Methods for Genome Scale Imaging of Brain Gene Expression (pp314-323)
Daniel M. Sforza and Desmond J. Smith - MR–Intracranial Compliance and Pressure: A Method for Noninvasive Measurement of Important Neurophysiologic Parameters (pp323-349)
Noam Alperin - Near-Infrared Spectroscopy and Imaging of Tumor Vascular Oxygenation (pp349-378)
Hanli Liu, Yueqing Gu, Jae G. Kim and Ralph P. Mason - Measuring Changes in Tumor Oxygenation (pp378-418)
Dawen Zhao, Lan Jiang and Ralph P. Mason
- Author Index (pp419-456 )
- Subject Index (pp457-465)